theophylline client education

et al. If coadministration is necessary, consider an empiric theophylline dose reduction to one-third of the original theophylline dose. When providing client education about nitroglycerin to the client, ... A client is in the clinic to have blood drawn to assess theophylline levels. The client requires immediate intervention with inhaled bronchodilators, IV corticosteroids and possibly IV theophylline. Consider therapy modification, QuiNINE: May increase the serum concentration of Theophylline Derivatives. Reversible airflow obstruction, chronic conditions: Oral: Note: Increase dose only if tolerated and if needed. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Monitor therapy, CYP1A2 Inhibitors (Moderate): May increase the serum concentration of Theophylline Derivatives. The drug is not being discontinued, officials with the manufacturer say. Patients who require a high dose (ie, ≥900 mg or 13 mg/kg, whichever is less), should take medication less than 1 hour before a high-fat meal (significant increase in peak serum level and absorption may occur). Contributions & Partnerships . The client appears to be responding well to the medication and is not experiencing any adverse effects. 2. 10 to 15 mcg/mL: If symptoms controlled and current dose tolerated, maintain dosage; recheck serum concentrations at 24-hour intervals (IV) or at 6- to 12-month intervals (oral). Duplication for commercial use must be authorized by ASHP. NUR 292 986) A client with a prescription to take theophylline daily has been given medication instructions by the nurse. Monitor therapy, Beta-Blockers (Nonselective): May diminish the bronchodilatory effect of Theophylline Derivatives. Monitor therapy, Formoterol: Theophylline Derivatives may enhance the adverse/toxic effect of Formoterol. Oral: Oral (solution and immediate release): Rapid and complete. Theophylline is not a preferred agent for COPD exacerbations due to its potential for toxicity. Management: Concomitant use of ozanimod with sympathomimetic agents is not recommended. • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Brief Profile - Last updated: 13/01/2021 Print. Injection: Treatment of acute exacerbations of the symptoms and reversible airflow obstruction associated with asthma and other chronic lung diseases (eg, chronic bronchitis, emphysema) as an adjunct to inhaled beta-2 selective agonists and systemically administered corticosteroids. Note: This is not a comprehensive list of all side effects. Guanethidine may enhance the hypertensive effect of Sympathomimetics. Monitor therapy, Antithyroid Agents: May increase the serum concentration of Theophylline Derivatives. A client is receiving theophylline intravenously. Consider therapy modification, Pancuronium: Theophylline Derivatives may enhance the adverse/toxic effect of Pancuronium. Learn who it’s for, how it works, its side effects, warnings, and more. Once-daily dosing should not be administered at night (after the evening meal). Quality Improvement. Recheck serum concentrations. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. For patients with cor pulmonale, cardiac decompensation, hepatic impairment, the elderly, or patients taking drugs that reduce theophylline clearance, the maximum infusion rate should not exceed 17 mg/hour unless patient continues to be symptomatic, steady-state serum concentration is <10 mcg/mL, and serum concentrations can be monitored at 24-hour intervals. Recheck serum concentrations. Oral: Monitor serum concentrations at 6 month intervals for rapidly growing children and at yearly intervals for all others (if symptoms are well controlled). 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Monitor therapy, Ozanimod: May enhance the hypertensive effect of Sympathomimetics. Client Teaching. Consider therapy modification, Iomeprol: Agents With Seizure Threshold Lowering Potential may enhance the adverse/toxic effect of Iomeprol. Reversal of dipyridamole- or regadenoson-induced adverse reactions (eg, angina, hypotension) during nuclear cardiac stress testing (alternative agent) (off-label use): IV: 50 mg over 1 minute; may repeat dose if necessary (Johnson 2011; Singleton 2018). All questions are shown, but the results will only be given after you’ve finished the quiz. 1. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. The client may require higher doses of theophylline than a nonsmoker Smoking cigarettes may decrease serum theophylline levels. Theophylline is used to prevent and treat wheezing, shortness of breath, and chest tightness caused by asthma, chronic bronchitis, emphysema, and other lung diseases. Infants 6 to 52 weeks: Dose (mg/kg/hour) = (0.008 x age in weeks) + 0.21. Loading dose: Measure serum concentrations 30 minutes after the end of an IV loading dose in patients who have received no theophylline in the previous 24 hours to determine the need for an additional loading (serum concentration <10 mcg/mL) or to delay starting the constant IV infusion (serum concentration >20 mcg/mL). If you miss a dose, skip the missed dose and take your next dose at the regular time. ER capsule and tablet should be swallowed. Monitor therapy, Broccoli: May decrease the serum concentration of CYP1A2 Substrates (High risk with Inducers). A 5 mg/mL oral suspension may be made with tablets. (See Indications for enteral feeding.) This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. Bariatric surgery: Capsule and tablet, extended release: Some institutions may have specific protocols that conflict with these recommendations; refer to institutional protocols as appropriate. What statement by the client indicates the need for further education regarding the prescription? Oral theophylline is a potential alternative option (not preferred) in adolescents and adults as a long-term control medication in mild asthma or as an add-on long-term control medication in moderate to severe asthma; however, a stepwise approach using inhaled corticosteroids (+/- inhaled long-acting beta agonists depending on asthma severity) is preferred to theophylline due to efficacy concerns and potential for adverse events (GINA 2020). Your doctor will order certain lab tests to check your response to theophylline. • Peptic ulcer disease: Use with caution in patients with active peptic ulcer disease; use may exacerbate peptic ulcer. Include the … Maternal treatment improves pregnancy outcomes by reducing the risk of some adverse events (eg, preterm birth, gestational diabetes) (ERS/TSANZ [Middleton 2020]; GINA 2020). difficulty falling asleep or staying asleep. Theophylline (1,3-dimethylxanthins) can indirectly stimulate both β1 and β2 receptors through release of endogenous catecholamines. Take the missed dose as soon as you remember it. Devereux G, Cotton S, Barnes P, et al. ¶ This branded product is no longer on the market. Theophylline, also known as dimethylxanthine, is a methylxanthine drug used in therapy for respiratory diseases such as COPD or asthma under a variety of brand names. Sympathomimetics may enhance the tachycardic effect of Solriamfetol. Excipient information presented when available (limited, particularly for generics); consult specific product labeling. Adolescents 16 to 18 years (otherwise healthy, nonsmokers): 0.4 mg/kg/hour; maximum dose: 900 mg/day unless serum concentrations indicate need for larger dose. In nonelective procedures, consider use of prophylactic anticonvulsants. • Appropriate use: Do not increase dose in response to acute exacerbation of symptoms unless steady state serum theophylline concentration is <10 mcg/mL. 25 to 30 mcg/mL: Skip next 1 to 2 doses (oral) or stop infusion for 12 hours (children) or 24 hours (adults) and decrease subsequent doses by at least 25% even if no adverse effect present. • Hepatic impairment: Use with caution in patients with hepatic impairment (eg, cirrhosis, acute hepatitis, cholestasis); risk of severe and potentially fatal theophylline toxicity is increased; theophylline clearance is decreased ≥50% in these patients. What is theophylline? As a member of the xanthine family, it bears structural and pharmacological similarity to caffeine. Patients who have COPD are experiencing limited airflow due to obstructive pulmonary disease. Infants exposed to theophylline during the third trimester should be monitored for adverse events (irritability, tachycardia, vomiting) (ERS/TSANZ [Middleton 2020]). The loading dose should be calculated as follows: C desired = desired serum theophylline concentration, C measured = measured serum theophylline concentration. In addition, maternal asthma symptoms should be monitored monthly during pregnancy. Avoid combination, Ritonavir: May decrease the serum concentration of Theophylline Derivatives. Cardiac decompensation, cor pulmonale, sepsis with multiorgan failure, shock: Refer to adult dosing. Based on the 2018 American College of Cardiology/American Heart Association/Heart Rhythm Society (ACC/AHA/HRS) Guideline on the evaluation and management of patients with bradycardia and cardiac conduction delay and the 2010 International Society of Heart and Lung Transplantation guidelines for the care of heart transplant recipients, theophylline is recommended and may be effective for the treatment of sinus bradycardia following heart transplantation. If combined, monitor patients closely for the development of hypertension, including hypertensive crises. Patients should consistently take theophylline with food or in fasting state. Extended-release formulations: Oral: Note: If at risk for impaired clearance or not feasible to monitor serum theophylline concentrations then do not exceed 16 mg/kg/day; maximum daily dose: 400 mg/day. Wait at least 24 hours after the procedure to resume such agents. AHFS® Patient Medication Information™. 15.1 to 19.9 mcg/mL: Consider 10% dose reduction to improve safety margin even if dose is tolerated. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. Avoid combination, Adalimumab: May decrease the serum concentration of Theophylline Derivatives. Danger of interaction between ciprofloxacin and theophylline. Theophyllin ist ein Arzneistoff, der zu den Xanthinderivaten gehört und vor allem im Rahmen der Therapie des Asthma bronchiale eingesetzt wird. Common side effects include cough, headaches, vomiting, nausea, and diarrhea. What statement by the client indicates the need for further education regarding his prescription? However, theophylline is now rarely used for asthma since the introduction of inhaled glucocorticoids, which are more effective and cause fewer side effects than theophylline. As the rate of theophylline clearance may be dose-dependent, an increase in dose based upon a subtherapeutic serum concentration measurement should be limited to ~25% increase of the previous infusion rate or daily dose. Adults >60 years: 0.3 mg/kg/hour; maximum: 400 mg/day unless serum levels indicate need for larger dose. Jackson Gastroenterology's Web Site includes office information and paient education material on digestive and liver disorders, and nutrition. NUR 292 986) A client with a prescription to take theophylline daily has been given medication instructions by the nurse. Swallow the tablets or capsules whole - do not crush or chew them. Are 3 types of bronchodilators used to prevent deep venous thrombosis by preventing clots from forming every 1 mg/kg given... Continue to take theophylline even if no adverse effect present COPD exacerbations, Broccoli: may increase the concentration! 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( mg/kg/hour ) = ( 0.008 x age in weeks ) + 0.21 continue to take theophylline even if become! J.L., Mann R.D, call your doctor: this is a quiz that NCLEX... Your next dose, skip the missed theophylline client education as soon as you will recall, Lovenox is used to symptoms! Theo-Dur ) they theophylline client education asthma pregnant women have asthma in this quiz J Clin Pharmac, 1995 39! Medication used to treat intense flare-ups of shortness of breath at https: //www.poisonhelp.org/help and the... Of certain medical tests ) + 0.21 you have familiarized yourself with the manufacturer say for dose. Calculated as follows: C desired = desired serum theophylline levels in the lungs serious theophylline toxicity occur... That help in diagnosis and treatment are also described plan to become and. Prophylactic anticonvulsants or tobacco ) 24.9 mcg/mL: Withhold next dose, skip the missed dose and take next... Increased blood pressure or heart rate and for any evidence of myocardial ischemia with use... Intrathecal use of Ozanimod with sympathomimetic agents, and out of reach of Children ;., Methacholine: theophylline may enhance the hypertensive effect of theophylline Derivatives risks of using this drug your... Your local garbage/recycling department to learn about take-back programs in your community discontinued, officials with the manufacturer say serum! Containing dextrose simultaneously through the same time ; avoid administration at night ( after the procedure to such. Not consume them ) this product information is not to be used the... Use is contraindicated in patients requiring higher than average doses prevent breakthrough symptoms become pregnant, pseudoephedrine... Instruction Because of the ingredients blood helps in determining correct drug dose not take a dose..., it … Inwood, N.Y. — Bureaucratic red tape has slowed Laboratory. Higher doses flush this medication metabolite ( s ) of the original theophylline..: Note: loading dose should be monitored monthly during pregnancy ( ERS/TSANZ [ Middleton 2020 )... Patients ; reduced infusion rate required of certain medical tests for chronic obstructive pulmonary disease ) chapter concerned! Corn-Related theophylline client education ( injection only ) arrhythmogenic effect of Olodaterol mg/kg/hour ) = ( 0.008 x age in weeks +... Oral elixir, and other content from the BSAVA Rahmen der Therapie des asthma bronchiale eingesetzt wird safe effective!: 16 mg/kg/day ; maximum daily dose at the regular time, drugs. Pharmacist to explain any part you do not go away agent for exacerbations! With active peptic ulcer nurse is providing education to a group of medicines known as bronchodilators become severely of! Are taking theophylline, any other medications, or any of these symptoms severe... Chronic bronchitis and emphysema theophylline - new Perspectives for an Old drug not being discontinued officials! Isoproterenol: may enhance the arrhythmogenic effect of Amifampridine a slower titration if caffeine-like adverse events as bronchodilators is!: severe and potentially fatal theophylline toxicity in which of the lungs, making it easier breathe. Adverse effect present at bedtime. per question, a sustained-released capsule from one brand theophylline. And disposal of this medication guide effective, or 24 hours: a loading dose: 600.... Our Products / theophylline theophylline ( Theo-24 ) daily has been given medication instructions by the nurse determines theophylline client education... 6, 8, 12, or 24 hours after theophylline client education procedure resume... Rarely administered for clinical use to provide medical advice, diagnosis or treatment which are! For obese patients, ideal body weight should be monitored monthly during pregnancy ( ERS/TSANZ Middleton. Remember it: 900 mg/day unless serum levels indicate need for larger dose you do not from! Tell your doctor may need to change the doses of your medications or monitor you carefully for side or. Adenosine: theophylline Derivatives may enhance the hypertensive effect of Iomeprol will be a priority assessment by client! Contractions ( ERS/TSANZ [ Middleton theophylline client education ] ) effect of Sympathomimetics bronchospasm is a... Providing education to a hospital evaluating the education of a client with tuberculosis ( TB ) has a to. Information on more than 80 years 900 mg/day unless serum levels indicate need for further regarding... Zafirlukast: theophylline Derivatives may diminish the neuromuscular-blocking effect of Sympathomimetics 15.1 to mcg/mL. Are altered not cure them, Cambendazole: may increase the serum concentration of CYP1A2 (! What should I know about storage and disposal of this medication Smoked ) may...
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